When to avoid. You should not take this medication if you are allergic to Ciprofloxacin or other fluoroquinolones. Tell your doctor if you are taking tizanidine (Zanaflex), as you will probably not be able to take Ciprofloxacin while you are taking this medication. Also tell your doctor if you have a history of myasthenia gravis. It is a good idea to give your doctor a list of all medications you are taking, including herbals and supplements, before starting Ciprofloxacin. This medication can increase the risk of developing tendinitis or having a tendon rupture; the risk is higher in those greater than 60 years old, taking steroid medications, and those who have had a lung, heart, or kidney transplant.
If you are taking certain medications, take ciprofloxacin at least 2 hours before or 6 hours after these medications: antacids that contain calcium, aluminum hydroxine, or magnesium hydroxide, didanosine (Videx) solution, iron, calcium or zinc supplements, phosphate binders including sevelamer (Renagel, Renvela) or lanthanum carbonate (Fosrenol), sucralfate (Carafate). These medications can lessen the effectiveness of Ciprofloxacin when taken together.