Outlook. Rhabdomyolysis can cause lasting damage to the kidneys and affected muscles. Prompt medical treatment is absolutely vital in preventing long-term damage. Treatment typically includes intravenous fluids, with more severe situations requiring short or long-term dialysis and/or hemofiltration. It is estimated that rhabdomyolysis results in 5-25% of all cases of Acute Kidney Injury. In addition to kidney failure, complications from rhabdomyolysis may also include greatly elevated potassium levels, decreased blood calcium and potentially compartment syndrome.