Prevention. The prevention of rhabdomyolysis focuses primarily on two components: Drinking Plenty of Fluids and Seeking Medical Attention Immediately upon suspected impact. Prior to any strenuous exercise, drinking plenty of fluids will dilute the concentration of myoglobin, assisting the kidney in clearing the bloodstream. It is imperative to drink fluids at the first sign of thirst, not waiting for the thirst to build. Rhabdomyolysis can have severe consequences if not handled in a accurate, prompt fashion. Education is always the best prevention.