Risk Factors. The factors that increase a man’s risk of developing a scrotal mass vary, as there many different causes of a scrotal abnormality. The most significant risk factor is undescended or retractile testicles. The former occurs when the testicles fail to drop from the abdominal cavity and into the scrotum, whereas the latter is the opposite: a retractile testicle does descend into the scrotum, but retreats back into the abdomen later. Having a personal or family history of testicular cancer will also increase a man’s risk of developing a mass.