Treatment. It’s important to note that not all masses will cause long-term complications, but only a doctor will be able to make this distinction. Most will only require a minimally invasive treatment, if any at all. However, some will need to be treated by medication or more serious procedures. The treatment will depend on the causes of the mass. Scrotal masses that develop as a result of an infection are treated with antibiotics. Noncancerous masses will either be left alone or surgically removed, depending on whether they cause discomfort or pain. In cancer cases, treatment will depend on how far the cancer has progressed and whether it is isolated to a testicle or has spread to the surrounding tissues. Radical inguinal orchiectomy is the primary treatment method for testicular cancer. This surgical procedure removes the affected testicle. Chemotherapy is also commonly utilized, as is radiation or X-ray therapies.