Risk Factors of Cardiovascular Disease. High blood pressure is one of the biggest risk factors for people when it comes to cardiovascular disease. There are however others. People who eat diets high in saturated fats or drink more than two alcoholic drinks per day are certainly at risk. People overweight or who don’t exercise daily also find themselves at higher risk. Diabetics and smokers are two groups at risk. Family history can be a warning sign. Finally, age is a risk factor. Men over the age of 45 and women over the age of 55 are at a higher risk of heart disease.